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Manufacture flow chart of Ginkgo biloba extract

November 30, 2020

Ginkgo Biloba Extract: USP40 24/6 Ginkgo Acid<1ppm, EP9.0 24/6 Ginkgo Acid<1ppm, Water soluble 24/6 1g/10ml,

Injection solution GA>2.2% GB>1.2% GC>1.2%

Application:

Ginkgo leaf extract is used to improve mental performance, increase the pain-free walking distance in peripheral arterial occlusive disease, and for vertigo and tinnitus. Other indications include (age-associated) cognitive impairment and quality of life improvement in mild dementia. Ginkgo leaf extracts may help to prevent symptoms related to altitude sickness.

  • Auxiliary hypolipidemic
  • Relieve eye fatigue
  • Help improve memory
  • Skin care
  • Used for Cosmetics

Shelf life: 3 years
Country of origin: China
Botanical Name:Ginkgo Biloba L.
Starting material: Ginkgo leaves
Part Used:GinkgoLeaves(dry)
Extraction solvent: Food grade ethanol
Extraction ratio: 50:1
Composition : 100% Ginkgo Biloba extract,no adding other carriers
Residual Solvent: Ethanol <= 0.5%
Standard: Chp2015
Package Size:25Kg/Drum
Storage:Protect from light and seal.

CHP SPECIFICATION SHEET

Item Specification Test Method
Appearance Light yellow-brown powder Visual
Identification
Identification A Should conform Chp2015 TLC
Identification B Should conform Chp2015 HPLC
Test
Limit of Ginkgolic Acid NMT 10mg/kg HPLC
Sophoricoside Should be negative HPLC
Loss on drying NMT 5.0% Limit test
Residue on ignition NMT 0.8% Limit test
Mesh 100% through 80 mesh
Heavy metal Should conform Chp2015 AAS
Free Aglycone
Quercetin NMT 10 mg/kg HPLC
Kaempferol NMT 10 mg/kg HPLC
Isorhamnetin NMT 4 mg/kg HPLC
Apex area ratio
Q: K 0.8-1.2 HPLC
I: Q >0.15 HPLC
Microbiological limit
Aerobic plate count NMT 10cfu/g Limit test
Mold&Yeast NMT 10cfu/g Limit test
E.Coli Negative Limit test
Assay
Content of flavonol glycosides 24%MIN HPLC
Quercetin / HPLC
Kaempferol / HPLC
Isorhamnetin / HPLC
Terpene lactones 6.0%MIN HPLC
Bilobalides / HPLC
Ginkgolides A / HPLC
Ginkgolides B / HPLC
Ginkgolides C / HPLC

 

 

 

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